What is ivermectin

To help avoid interactions, your doctor should manage all of your medications carefully. Warfarin is a drug used to thin your blood. Taking warfarin with ivermectin can thin your blood too much and cause dangerous bleeding.

If you need to take these drugs together, your doctor will monitor your international normalized ratio INR. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. Always speak with your healthcare professional about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

Taking it again could be fatal cause death. For people with asthma : This drug may make your asthma worse. Ask your doctor if this drug is safe for you. For people with liver problems: If you have liver problems or a history of liver issues, this drug may cause more harm to your liver. Also, you may not be able to process this drug well. This may increase the levels of the drug in your body and cause more side effects. For people with seizures: This drug may cause seizures.

You may need several treatments with this drug. For pregnant women: Ivermectin is a category C pregnancy drug. That means two things:. This drug should only be used if the potential benefit justifies the potential risk. For women who are breastfeeding: Ivermectin passes into breast milk and may cause side effects in a child who is breastfed. Talk with your doctor if you breastfeed your child. You may need to decide whether to stop breastfeeding or stop taking this medication.

For seniors: Your liver may not work as well as it used to. This can cause your body to process drugs more slowly. As a result, more of this drug can stay in your body for a longer time. This raises your risk of side effects. All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:. Your liver may not work as well as it used to.

However, because drugs affect each person differently, we cannot guarantee that this list includes all possible dosages. Always speak with your doctor or pharmacist about dosages that are right for you. Ivermectin oral tablet is used for short-term treatment. However, if you take too much or your dose is too high, you could have dangerous levels of this drug in your body.

Symptoms of an overdose of this drug can include:. If your symptoms are severe, call or go to the nearest emergency room right away. How to tell if the drug is working: Your symptoms should improve. Your doctor will do tests to make sure this drug is working to treat your infection. Since ivermectin is usually given in a single dose, you may not be on a dosing schedule. If you are on a schedule, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose.

Do not take extra medicine to make up the missed dose. Get emergency medical help if you have signs of an allergic reaction : hives; difficult breathing; swelling of your face, lips, tongue, or throat. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Other drugs may interact with ivermectin, including prescription and over-the-counter medicines, vitamins, and herbal products.

Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise.

Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides.

The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. This information does not replace the advice of a doctor. Healthwise, Incorporated, disclaims any warranty or liability for your use of this information.

Your use of this information means that you agree to the Terms of Use. Patients received various concomitant medications e. This confounded the assessment of the efficacy or safety of ivermectin. The study outcome measures were not always clearly defined. Adverse effects may include dizziness, pruritis, nausea, or diarrhea.

Neurological adverse effects have been reported with the use of ivermectin for the treatment of onchocerciasis and other parasitic diseases, but it is not clear whether these adverse effects were caused by ivermectin or the underlying conditions. Ivermectin is generally given on an empty stomach with water; however, administering ivermectin with food increases its bioavailability.

Please see Table 2c for additional information. Considerations in Pregnancy In animal studies, ivermectin was shown to be teratogenic when given in doses that were maternotoxic. Clinical Trials Several clinical trials that are evaluating the use of ivermectin for the treatment of COVID are currently underway or in development. References Omura S, Crump A. Ivermectin: panacea for resource-poor communities? Trends Parasitol. Toxicity of bloodmeals from ivermectin-treated cattle to Anopheles gambiae s.

Ann Trop Med Parasitol. Over 25 years of clinical experience with ivermectin: an overview of safety for an increasing number of indications. J Drugs Dermatol. Antiviral Res. Ivermectin reduces coronavirus infection in vivo: a mouse experimental model.

Lehrer S, Rheinstein PH. In Vivo. Biochem J. A screen of FDA-approved drugs for inhibitors of Zika virus infection. Cell Host Microbe. Inflamm Res. Open Heart. Avermectin exerts anti-inflammatory effect by downregulating the nuclear transcription factor kappa-B and mitogen-activated protein kinase activation pathway.